Basic Information
ID: ALA3998490
Type: Binding
Description: Antagonist activity at recombinant human glycine receptor alpha 1 beta expressed in HEK293 cells assessed as inhibition of glycine-induced current at -50mV holding potential by whole cell patch-clamp method
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Glycine receptor (alpha-1/beta)(ALA2363052)
Document: ALA3997776
Antagonist activity at recombinant human glycine receptor alpha 1 beta expressed in HEK293 cells assessed as inhibition of glycine-induced current at -50mV holding potential by whole cell patch-clamp method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3998490
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 334.42 | 2.09 | 2.09 |
| 349.43 | 1.67 | 1.67 |
| 405.50 | 2.49 | 2.49 |
| 457.41 | 3.02 | 3.02 |
| 403.48 | 2.26 | 2.26 |
| 363.42 | 1.53 | 1.53 |
| 405.50 | 2.44 | 2.44 |
| 377.44 | 1.70 | 1.70 |
| 401.47 | 1.71 | 1.71 |