Basic Information
ID: ALA3998554
Type: Binding
Description: Inhibition of recombinant human DNA-topoisomerase 2 assessed as decrease in supercoiled pHOT DNA relaxation at 20 uM after 30 to 45 mins by ethidium bromide staining-based agarose gel electrophoresis method relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3998554
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 362.40 | 3.98 | 3.98 |
| 296.37 | 2.74 | 2.74 |
| 344.41 | 3.84 | 3.84 |
| 296.37 | 2.50 | 2.50 |
| 376.43 | 3.99 | 3.99 |
| 310.40 | 2.75 | 2.75 |
| 358.44 | 3.85 | 3.85 |
| 282.34 | 2.49 | 2.49 |