Basic Information
ID: ALA3998557
Type: Binding
Description: Inhibition of recombinant human DNA-topoisomerase 2 assessed as decrease in supercoiled pHOT DNA relaxation at 12.5 to 100 uM after 30 to 45 mins by ethidium bromide staining-based agarose gel electrophoresis method
Format: BAO_0000357
Organism: Homo sapiens
Target: DNA topoisomerase II alpha(ALA1806)
Document: ALA3997781
Inhibition of recombinant human DNA-topoisomerase 2 assessed as decrease in supercoiled pHOT DNA relaxation at 12.5 to 100 uM after 30 to 45 mins by ethidium bromide staining-based agarose gel electrophoresis method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3998557
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 296.37 | 2.50 | 2.50 |
| 358.44 | 3.85 | 3.85 |