Basic Information
ID: ALA3998890
Type: Binding
Description: Selectivity ratio of IC50 for human KDAC8 to IC50 for human KDAC6
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3998890
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 264.32 | 2.47 | 2.47 |
| 302.37 | 2.58 | 2.58 |
| 236.27 | 2.48 | 2.48 |
| 376.42 | 3.34 | 3.34 |
| 250.30 | 2.86 | 2.86 |
| 349.43 | 3.33 | 3.33 |
| 622.88 | 5.03 | 5.03 |
| 326.40 | 4.09 | 4.09 |
| 278.36 | 3.50 | 3.50 |
| 335.23 | 3.41 | 3.41 |
| 335.41 | 2.80 | 2.80 |
| 296.33 | 2.82 | 2.82 |
| 389.48 | 4.08 | 4.08 |
| 322.41 | 3.66 | 3.66 |
| 394.43 | 2.97 | 2.97 |
| 453.61 | 4.45 | 4.45 |
| 310.42 | 3.60 | 3.60 |
| 532.69 | 2.63 | 2.63 |
| 470.57 | 5.10 | 5.10 |
| 422.49 | 2.18 | 2.18 |
| 408.46 | 2.03 | 2.03 |
| 464.56 | 4.62 | 4.62 |
| 294.31 | 2.32 | 2.32 |
| 673.82 | 7.19 | 7.19 |
| 452.62 | 5.11 | 5.11 |
| 649.79 | 7.08 | 7.08 |
| 378.47 | 4.15 | 4.15 |
| 392.50 | 4.24 | 4.24 |
| 436.55 | 4.40 | 4.40 |
| 480.57 | 4.64 | 4.64 |
| 450.54 | 2.18 | 2.18 |
| 465.55 | 3.65 | 3.65 |
| 587.75 | 4.77 | 4.77 |
| 364.45 | 3.60 | 3.60 |
| 687.86 | 5.42 | 5.42 |
| 406.53 | 4.63 | 4.63 |
| 308.34 | 2.71 | 2.71 |
| 350.42 | 3.51 | 3.51 |
| 407.51 | 4.54 | 4.54 |
| 323.35 | 2.13 | 2.13 |
| 424.46 | 1.81 | 1.81 |
| 484.60 | 5.19 | 5.19 |
| 465.55 | 5.83 | 5.83 |
| 370.45 | 4.45 | 4.45 |
| 478.59 | 4.70 | 4.70 |
| 365.43 | 2.93 | 2.93 |
| 422.53 | 4.31 | 4.31 |
| 395.46 | 2.30 | 2.30 |
| 393.49 | 3.57 | 3.57 |
| 392.50 | 4.54 | 4.54 |
| 338.48 | 4.38 | 4.38 |
| 309.33 | 1.74 | 1.74 |
| 513.64 | 5.33 | 5.33 |
| 565.67 | 6.47 | 6.47 |
| 440.54 | 4.83 | 4.83 |
| 521.66 | 5.28 | 5.28 |
| 350.42 | 3.21 | 3.21 |
| 437.54 | 3.73 | 3.73 |
| 672.83 | 7.86 | 7.86 |
| 479.58 | 4.04 | 4.04 |
| 431.50 | 2.88 | 2.88 |
| 425.55 | 3.67 | 3.67 |
| 408.46 | 1.79 | 1.79 |
| 522.65 | 4.61 | 4.61 |
| 292.38 | 3.89 | 3.89 |
| 409.44 | 2.39 | 2.39 |
| 649.79 | 7.38 | 7.38 |
| 394.43 | 1.64 | 1.64 |
| 364.45 | 3.97 | 3.97 |
| 292.38 | 3.89 | 3.89 |
| 364.45 | 3.97 | 3.97 |
| 392.50 | 4.54 | 4.54 |
| 350.42 | 3.58 | 3.58 |
| 549.67 | 6.73 | 6.73 |
| 507.63 | 5.19 | 5.19 |
| 423.47 | 2.78 | 2.78 |
| 407.51 | 3.96 | 3.96 |
| 351.41 | 2.55 | 2.55 |
| 410.54 | 4.25 | 4.25 |
| 512.65 | 6.00 | 6.00 |
| 309.33 | 1.74 | 1.74 |
| 426.52 | 4.74 | 4.74 |
| 424.57 | 4.34 | 4.34 |
| 650.78 | 6.41 | 6.41 |
| 635.76 | 6.99 | 6.99 |
| 464.56 | 4.31 | 4.31 |
| 485.58 | 4.52 | 4.52 |
| 457.53 | 3.86 | 3.86 |
| 323.35 | 2.13 | 2.13 |
| 580.69 | 5.90 | 5.90 |
| 558.69 | 7.12 | 7.12 |
| 397.50 | 2.84 | 2.84 |
| 498.62 | 5.91 | 5.91 |
| 381.43 | 1.91 | 1.91 |
| 664.81 | 6.80 | 6.80 |
| 579.70 | 6.56 | 6.56 |
| 350.42 | 3.58 | 3.58 |
| 398.51 | 5.26 | 5.26 |
| 450.54 | 4.23 | 4.23 |
| 535.65 | 6.34 | 6.34 |
| 336.39 | 3.13 | 3.13 |
| 408.45 | 3.36 | 3.36 |
| 663.82 | 7.47 | 7.47 |
| 441.53 | 4.16 | 4.16 |
| 422.53 | 3.04 | 3.04 |
| 701.89 | 5.50 | 5.50 |
| 406.53 | 4.63 | 4.63 |
| 308.34 | 2.71 | 2.71 |
| 438.48 | 2.20 | 2.20 |
| 438.59 | 5.03 | 5.03 |
| 407.51 | 3.96 | 3.96 |
| 294.31 | 2.32 | 2.32 |
| 702.88 | 4.84 | 4.84 |
| 658.80 | 7.77 | 7.77 |