Basic Information
ID: ALA3998959
Type: Binding
Description: Inhibition of human liver CES1 expressed in U373MG cells assessed as oseltamivir carboxylate formation at 5 uM using oseltamivir as substrate preincubated for 30 mins followed by compound washout and subsequent compound/substrate addition measured after 30 mins by UPLC-MS method relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3998959
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 242.27 | 2.75 | 2.75 |
| 263.30 | 2.93 | 2.93 |
| 250.25 | 2.87 | 2.87 |
| 280.28 | 2.88 | 2.88 |
| 268.24 | 3.01 | 3.01 |
| 293.32 | 2.94 | 2.94 |
| 284.70 | 3.53 | 3.53 |
| 297.74 | 3.58 | 3.58 |
| 277.32 | 3.24 | 3.24 |
| 342.19 | 3.69 | 3.69 |
| 329.15 | 3.63 | 3.63 |
| 264.28 | 3.18 | 3.18 |
| 281.29 | 3.07 | 3.07 |