Assay Report Card

Basic Information

ID: ALA3999011

Type: Binding

Description: Inhibition of full length recombinant human N-terminal His6-tagged PI3Kalpha (1 to 1068 residues)/full length human N-terminal myc-tagged P85alpha (1 to 724 residues) expressed in Sf9 insect cells assessed as residual activity at 100 uM using PI : PS as substrate in presence of [gamma-33P]-ATP by scintillation counting method relative to control

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
372.484.484.48
414.565.515.51
360.464.294.29
330.444.284.28
430.565.875.87
426.455.025.02
434.555.775.77
372.484.484.48
386.504.874.87