Assay Report Card

Basic Information

ID: ALA3999024

Type: Binding

Description: Corrector activity at CFTR F508 deletion mutant (unknown origin) expressed in HEK293 cells assessed as increase in steady-state level of F508 deletion mutant at plasma membrane at 10 uM preincubated for 24 hrs followed by compound washout by pHTomato dye based fluorescence imaging method

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
430.565.875.87
434.555.775.77
386.504.874.87