Basic Information
ID: ALA3999063
Type: Binding
Description: Inhibition of 5'-biotin-labeled c-Myc Pu18 G-quadruplex DNA (unknown origin) interaction with His-tagged NM23-H2 assessed as ratio of Kd for NM23-H2-DNA complex in presence of compound to Kd for NM2-H2-DNA complex in absence of compound at 20 uM preincubated with NM23-H2 for 1 hr followed by addition of DNA measured after overnight incubation by ELISA
Organism: Not specified
Activity Charts
Bioactivity
Activity Types for Assay ALA3999063
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 554.70 | 4.19 | 4.19 |
| 544.68 | 3.45 | 3.45 |
| 530.65 | 3.66 | 3.66 |
| 529.66 | 5.28 | 5.28 |
| 560.72 | 4.45 | 4.45 |
| 558.70 | 4.20 | 4.20 |
| 568.72 | 4.58 | 4.58 |
| 532.66 | 3.90 | 3.90 |
| 589.72 | 2.17 | 2.17 |
| 515.63 | 4.89 | 4.89 |
| 517.65 | 5.14 | 5.14 |
| 532.66 | 3.30 | 3.30 |
| 544.68 | 4.05 | 4.05 |