Basic Information
ID: ALA3999826
Type: Binding
Description: Reversible inhibition of Sporosarcina pasteurii CCM 2056 urease assessed as reduction in ammonia production by measuring recovery of enzyme activity at 10 times IC50 preincubated for 60 mins followed by 100-fold dilution in to PBS containing urea as substrate by Berthelot colorimetric assay relative to control
Organism: Sporosarcina pasteurii
Strain: CCM 2056
Activity Charts
Bioactivity
Activity Types for Assay ALA3999826
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 75.07 | -0.49 | -0.49 |
| 148.16 | 1.78 | 1.78 |
| 190.20 | 1.82 | 1.82 |
| 82.10 | 0.91 | 0.91 |
| 193.16 | 1.69 | 1.69 |
| 176.21 | 2.26 | 2.26 |
| 174.11 | -0.44 | -0.44 |
| 162.19 | 2.09 | 2.09 |
| 116.07 | -0.29 | -0.29 |
| 116.07 | -0.29 | -0.29 |
| 70.05 | -0.30 | -0.30 |
| 96.13 | 1.30 | 1.30 |
| 144.13 | 0.19 | 0.19 |
| 114.06 | -0.84 | -0.84 |
| 174.20 | 1.60 | 1.60 |
| 144.13 | -0.11 | -0.11 |
| 144.13 | -0.11 | -0.11 |
| 172.18 | 0.67 | 0.67 |
| 228.29 | 2.23 | 2.23 |
| 142.11 | -0.66 | -0.66 |
| 146.14 | 1.12 | 1.12 |
| 228.29 | 2.23 | 2.23 |
| 204.22 | 1.99 | 1.99 |
| 190.24 | 2.57 | 2.57 |
| 180.20 | 1.40 | 1.40 |
| 200.23 | 1.45 | 1.45 |
| 84.07 | 0.09 | 0.09 |
| 112.13 | 0.89 | 0.89 |
| 164.20 | 1.81 | 1.81 |
| 200.23 | 1.45 | 1.45 |
| 166.18 | 1.00 | 1.00 |
| 84.07 | -0.21 | -0.21 |
| 170.16 | 0.12 | 0.12 |
| 147.18 | 1.75 | 1.75 |
| 226.28 | 3.10 | 3.10 |
| 112.13 | 0.57 | 0.57 |
| 200.19 | 0.24 | 0.24 |
| 166.18 | 1.31 | 1.31 |
| 173.22 | 1.64 | 1.64 |
| 221.21 | 2.17 | 2.17 |
| 216.19 | -0.18 | -0.18 |