Drug metabolism in human liver microsomes assessed as glutathione reactivity by measuring sulfhydryl adduct formation at 500 uM after 60 mins in prese...

Basic Information

ID: ALA3999936

Type: ADME

Description: Drug metabolism in human liver microsomes assessed as glutathione reactivity by measuring sulfhydryl adduct formation at 500 uM after 60 mins in presence of [13C2,15N-Gly]GSH and NADPH generating system by LC-MS/MS analysis

Format: BAO_0000019

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction:  microsome

Target:  Liver(ALA613419)

Document:  ALA3997845

Drug metabolism in human liver microsomes assessed as glutathione reactivity by measuring sulfhydryl adduct formation at 500 uM after 60 mins in presence of [13C2,15N-Gly]GSH and NADPH generating system by LC-MS/MS analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
389.14
402.14
436.58