Basic Information
ID: ALA4000087
Type: Functional
Description: Agonist activity at TGR5 in human NCI-H716 cells assessed as increase in cAMP accumulation after 40 mins by HTRF assay
Format: BAO_0000219
Organism: Homo sapiens
Target: G-protein coupled bile acid receptor 1(ALA5409)
Document: ALA3997854
Agonist activity at TGR5 in human NCI-H716 cells assessed as increase in cAMP accumulation after 40 mins by HTRF assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4000087
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 525.60 | 6.64 | 6.64 |
| 524.61 | 7.24 | 7.24 |
| 541.06 | 7.76 | 7.76 |
| 531.46 | 8.23 | 8.23 |
| 561.48 | 7.37 | 7.37 |
| 527.04 | 7.58 | 7.58 |
| 527.04 | 7.58 | 7.58 |
| 515.00 | 7.71 | 7.71 |
| 561.48 | 8.24 | 8.24 |
| 568.66 | 6.78 | 6.78 |
| 531.46 | 8.23 | 8.23 |
| 531.46 | 8.23 | 8.23 |
| 565.90 | 8.88 | 8.88 |
| 704.26 | 7.86 | 7.86 |
| 533.43 | 7.42 | 7.42 |
| 599.45 | 9.25 | 9.25 |
| 547.91 | 8.74 | 8.74 |
| 478.57 | 5.88 | 5.88 |
| 699.84 | 7.22 | 7.22 |
| 525.02 | 7.34 | 7.34 |
| 527.04 | 7.58 | 7.58 |
| 490.60 | 5.75 | 5.75 |
| 545.48 | 8.40 | 8.40 |
| 559.51 | 8.79 | 8.79 |
| 515.00 | 7.71 | 7.71 |
| 542.01 | 7.48 | 7.48 |
| 549.45 | 8.37 | 8.37 |
| 568.62 | 6.94 | 6.94 |
| 743.85 | 6.01 | 6.01 |
| 545.48 | 8.53 | 8.53 |
| 563.47 | 8.35 | 8.35 |
| 497.01 | 7.57 | 7.57 |
| 575.91 | 8.34 | 8.34 |
| 527.04 | 7.58 | 7.58 |
| 549.45 | 8.37 | 8.37 |
| 543.49 | 8.10 | 8.10 |
| 704.26 | 7.86 | 7.86 |
| 687.80 | 7.35 | 7.35 |
| 516.97 | 6.91 | 6.91 |
| 529.01 | 6.78 | 6.78 |
| 529.03 | 7.89 | 7.89 |
| 495.02 | 6.40 | 6.40 |
| 515.00 | 7.71 | 7.71 |
| 510.99 | 7.29 | 7.29 |
| 515.00 | 7.71 | 7.71 |