Basic Information
ID: ALA4000100
Type: Binding
Description: Antagonist activity at DP2 receptor in human isolated eosinophils assessed as inhibition of DK-PGD2-induced shape change preincubated for 5 mins followed by DK-PGD2 addition measured after 5 mins by flow cytometry
Format: BAO_0000357
Organism: Homo sapiens
Target: G protein-coupled receptor 44(ALA5071)
Document: ALA3997855
Antagonist activity at DP2 receptor in human isolated eosinophils assessed as inhibition of DK-PGD2-induced shape change preincubated for 5 mins followed by DK-PGD2 addition measured after 5 mins by flow cytometry: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4000100
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 358.42 | 2.42 | 2.42 |
| 426.42 | 3.44 | 3.44 |
| 416.32 | 5.06 | 5.06 |
| 386.47 | 3.20 | 3.20 |
| 406.89 | 3.47 | 3.47 |
| 440.44 | 3.83 | 3.83 |
| 372.45 | 2.73 | 2.73 |
| 392.86 | 3.08 | 3.08 |
| 426.42 | 3.44 | 3.44 |
| 372.45 | 2.73 | 2.73 |
| 392.86 | 3.08 | 3.08 |
| 372.45 | 2.81 | 2.81 |
| 372.45 | 2.73 | 2.73 |
| 386.47 | 2.99 | 2.99 |
| 357.43 | 3.03 | 3.03 |
| 437.32 | 3.19 | 3.19 |