Basic Information
ID: ALA4000781
Type: ADME
Description: Metabolic stability in Wistar rat liver S9 fraction assessed as UGT-mediated glucuronidation of compound by measuring compound remaining at 5 uM preincubated for 3 mins followed by UDPGA addition measured after 60 mins by HPLC/MS analysis
Organism: Rattus norvegicus
Strain: Wistar
Tissue: Liver
Subcellular Fraction: S9
Activity Charts
Bioactivity
Activity Types for Assay ALA4000781
Stability
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 296.15 | 4.36 | 4.36 |
| 421.54 | 5.89 | 5.89 |
| 471.51 | 5.62 | 5.62 |
| 491.63 | 6.87 | 6.87 |
| 519.68 | 7.65 | 7.65 |
| 521.61 | 5.94 | 5.94 |
| 549.66 | 6.72 | 6.72 |
| 535.68 | 6.63 | 6.63 |
| 521.65 | 6.50 | 6.50 |
| 507.63 | 5.85 | 5.85 |
| 491.63 | 6.73 | 6.73 |
| 549.71 | 7.28 | 7.28 |