Basic Information
ID: ALA4001128
Type: Binding
Description: Inhibition of dynamin 2 in human U2OS cells assessed as reduction in clathrin-mediated endocytosis by measuring transferrin-A594 uptake preincubated for 30 mins followed by Tfn-A594 addition for 8 mins by DAPI staining based HTS assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4001128
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 279.43 | 2.75 | 2.75 |
| 277.42 | 2.50 | 2.50 |
| 279.43 | 2.75 | 2.75 |
| 391.65 | 5.87 | 5.87 |
| 320.53 | 5.18 | 5.18 |
| 321.51 | 4.00 | 4.00 |
| 349.57 | 4.78 | 4.78 |
| 321.51 | 4.00 | 4.00 |
| 307.49 | 3.53 | 3.53 |
| 307.49 | 3.53 | 3.53 |
| 349.57 | 4.78 | 4.78 |
| 335.54 | 4.31 | 4.31 |