Basic Information
ID: ALA4001394
Type: Functional
Description: In vivo inhibition of ERK1/2 phosphorylation at Thr202/Tyr204 residue in NOD/SCID mouse tumor xenografted with HER2-amplified human HCC1954 cells at 10 mg/kg, ip administered once daily for 18 days measured after 1 hr last dose by hematoxylin and eosin staining based microscopic method
Format: BAO_0000218
Organism: Mus musculus
Target: Mus musculus(ALA375)
Document: ALA4000195
In vivo inhibition of ERK1/2 phosphorylation at Thr202/Tyr204 residue in NOD/SCID mouse tumor xenografted with HER2-amplified human HCC1954 cells at 10 mg/kg, ip administered once daily for 18 days measured after 1 hr last dose by hematoxylin and eosin staining based microscopic method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4001394
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 387.47 | 5.13 | 5.13 |