Basic Information
ID: ALA4001639
Type: ADME
Description: Drug metabolism in human liver microsomes assessed as covalent binding per mg protein at 10 uM preincubated for 5 mins followed by NADPH addition measured after 30 mins by liquid scintillation counting
Format: BAO_0000019
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: microsome
Target: Liver(ALA613419)
Document: ALA4000210
Drug metabolism in human liver microsomes assessed as covalent binding per mg protein at 10 uM preincubated for 5 mins followed by NADPH addition measured after 30 mins by liquid scintillation counting: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4001639
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 606.70 | 4.76 | 4.76 |
| 640.69 | 4.29 | 4.29 |
| 641.68 | 3.69 | 3.69 |
| 610.69 | 3.42 | 3.42 |
| 625.73 | 4.57 | 4.57 |
| 605.67 | 4.22 | 4.22 |
| 623.73 | 4.66 | 4.66 |