Basic Information
ID: ALA4001768
Type: Binding
Description: Inhibition of N-terminal 6His/TEV protease cleavage site-tagged human EGFR L858R/T790M double mutant (696 to 1022 residues) using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISA
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4001768
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 499.62 | 4.51 | 4.51 |
| 555.56 | 4.78 | 4.78 |
| 525.61 | 3.72 | 3.72 |
| 473.56 | 3.40 | 3.40 |
| 484.56 | 3.42 | 3.42 |
| 593.61 | 4.74 | 4.74 |
| 553.67 | 4.49 | 4.49 |
| 503.61 | 2.56 | 2.56 |
| 539.64 | 4.03 | 4.03 |
| 621.66 | 5.51 | 5.51 |
| 567.69 | 4.84 | 4.84 |
| 458.53 | 2.72 | 2.72 |
| 539.64 | 4.03 | 4.03 |
| 496.58 | 3.10 | 3.10 |
| 543.60 | 3.86 | 3.86 |
| 539.64 | 4.11 | 4.11 |
| 503.61 | 2.56 | 2.56 |
| 604.51 | 4.48 | 4.48 |
| 581.72 | 5.02 | 5.02 |
| 517.63 | 2.64 | 2.64 |
| 517.63 | 2.95 | 2.95 |
| 553.67 | 4.28 | 4.28 |
| 607.64 | 5.12 | 5.12 |
| 560.06 | 4.37 | 4.37 |