Basic Information
ID: ALA4001886
Type: Binding
Description: Inhibition of Clostridium botulinum Hall BoNT/A light chain-induced paralysis in CD1 mouse phrenic nerve diaphragm assessed as compound concentration required to cause delay in time to 50% loss of twitch tension evoked by nerve stimulation preincubated with BoNT/A light chain for 15 to 20 mins followed by addition to diaphragm
Organism: Clostridium botulinum A str. Hall
Activity Charts
Bioactivity
Activity Types for Assay ALA4001886
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 345.38 | 4.68 | 4.68 |
| 341.41 | 4.85 | 4.85 |
| 327.39 | 4.54 | 4.54 |
| 345.38 | 4.68 | 4.68 |
| 361.83 | 5.19 | 5.19 |
| 379.82 | 5.33 | 5.33 |
| 345.38 | 4.68 | 4.68 |
| 359.40 | 4.98 | 4.98 |
| 377.39 | 5.12 | 5.12 |
| 397.81 | 5.47 | 5.47 |
| 379.82 | 5.33 | 5.33 |
| 359.40 | 4.98 | 4.98 |
| 359.40 | 4.98 | 4.98 |
| 363.37 | 4.82 | 4.82 |
| 380.81 | 4.72 | 4.72 |
| 361.83 | 5.19 | 5.19 |
| 379.82 | 5.33 | 5.33 |
| 346.37 | 4.07 | 4.07 |
| 377.39 | 5.12 | 5.12 |
| 397.81 | 5.47 | 5.47 |
| 362.82 | 4.59 | 4.59 |
| 379.82 | 5.33 | 5.33 |
| 363.37 | 4.82 | 4.82 |
| 360.39 | 4.38 | 4.38 |
| 359.40 | 4.98 | 4.98 |
| 341.41 | 4.85 | 4.85 |
| 327.39 | 4.54 | 4.54 |
| 380.81 | 4.72 | 4.72 |
| 345.38 | 4.68 | 4.68 |