Basic Information
ID: ALA4002327
Type: Binding
Description: Displacement of ovine [125-I]-CRF from human CRF1 receptor expressed in CHO cell membranes preincubated for 1 hr followed by compound washout for 2 hrs and subsequent addition of [125I]-CRF measured after 1 hr by liquid scintillation counting method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4002327
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 380.54 | 4.41 | 4.41 |
| 340.43 | 3.33 | 3.33 |
| 411.76 | 7.54 | 7.54 |