Assay Report Card

Basic Information

ID: ALA4002669

Type: Binding

Description: Chaperone activity assessed as enhancement of alpha GAL-A N215S mutant enzyme activity in Fabry patient derived lymphocytes up to 100 uM at pH 4.6 pretreated for 4 days followed by 4MU-alpha-galactopyranoside substrate addition in presence of N-acetylgalactosamine measured after 1 hr by fluorescence assay

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
163.17-2.97-2.97
163.17-2.97-2.97
360.33-0.11-0.11
384.43-1.18-1.18
328.450.300.30
401.26-0.36-0.36