Basic Information
ID: ALA4002791
Type: Functional
Description: Antitumor activity against FGFR1-amplified human NCI-H1581 cells xenografted in nude mouse assessed as tumor growth inhibition at 20 mg/kg, po qd administered for 10 days and measured on day 10 post last dose relative to vehicle-treated control
Format: BAO_0000218
Organism: Homo sapiens
Cell type: NCI-H1581
Target: NCI-H1581(ALA1075516)
Document: ALA4002548
Antitumor activity against FGFR1-amplified human NCI-H1581 cells xenografted in nude mouse assessed as tumor growth inhibition at 20 mg/kg, po qd administered for 10 days and measured on day 10 post last dose relative to vehicle-treated control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4002791
TGI
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 463.58 | 3.65 | 3.65 |
| 598.07 | 4.99 | 4.99 |