Basic Information
ID: ALA4002822
Type: ADME
Description: Inhibition of platelet NHE1 in human platelet rich plasma assessed as decrease in platelet swelling preincubated for 3 mins followed by sodium propionate addition measured after 4 mins by spectrophotometric method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4002822
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 229.63 | -1.08 | -1.08 |
| 283.35 | 0.63 | 0.63 |
| 119.13 | 0.96 | 0.96 |
| 161.21 | 1.84 | 1.84 |
| 175.23 | 2.23 | 2.23 |
| 189.26 | 2.62 | 2.62 |
| 223.24 | 2.12 | 2.12 |
| 209.25 | 2.48 | 2.48 |
| 133.15 | 0.97 | 0.97 |
| 195.65 | 2.06 | 2.06 |
| 133.15 | 0.97 | 0.97 |
| 273.32 | 1.98 | 1.98 |
| 175.23 | 2.23 | 2.23 |
| 203.29 | 3.01 | 3.01 |
| 278.14 | 3.79 | 3.79 |
| 147.18 | 1.45 | 1.45 |
| 217.32 | 3.40 | 3.40 |
| 195.65 | 2.06 | 2.06 |
| 189.26 | 2.62 | 2.62 |
| 161.21 | 1.84 | 1.84 |
| 203.29 | 3.01 | 3.01 |
| 259.29 | 1.67 | 1.67 |
| 147.18 | 1.45 | 1.45 |
| 217.32 | 3.40 | 3.40 |