Basic Information
ID: ALA4003456
Type: Binding
Description: Inhibition of JAK in human PBMC assessed as reduction in human recombinant IL-2/ mouse anti-human CD3 stimulated STAT5 phosphorylation at tyrosine residue preincubated for 1 hr followed by IL2/CD3 stimulation after 30 mins by immunofluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4003456
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 342.45 | 2.32 | 2.32 |
| 498.61 | 2.48 | 2.48 |