Basic Information
ID: ALA4003483
Type: Binding
Description: Inhibition of JAK1/TYK2 in human whole blood lymphocytes assessed as inhibition of IFNalpha induced STAT3 phosphorylation by measuring free compound concentration required for the effect preincubated for 45 mins followed by IFNalpha addition and measured after 20 mins by flow cytometric analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4003483
fIC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 566.64 | 5.01 | 5.01 |