Basic Information
ID: ALA4003484
Type: Binding
Description: Inhibition of JAK2/TYK2 in human whole blood lymphocytes assessed as inhibition of IL-23 induced STAT3 phosphorylation by measuring free compound concentration required for the effect preincubated for 45 mins followed by IL23 addition and measured after 20 mins by flow cytometric analysis
Format: BAO_0000219
Organism: Homo sapiens
Target: JAK1/TYK2(ALA3301391)
Document: ALA4002590
Inhibition of JAK2/TYK2 in human whole blood lymphocytes assessed as inhibition of IL-23 induced STAT3 phosphorylation by measuring free compound concentration required for the effect preincubated for 45 mins followed by IL23 addition and measured after 20 mins by flow cytometric analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4003484
fIC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 566.64 | 5.01 | 5.01 |