Basic Information
ID: ALA4003505
Type: Binding
Description: Time-dependent inhibition of JAK in human PBMC assessed as reduction in human recombinant IL-2/ mouse anti-human CD3 stimulated STAT5 phosphorylation at tyrosine residue at 10-fold IC50 preincubated with cells followed by compound washout and subsequent IL2/CD3 stimulation by immunofluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4003505
TDI
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 354.41 | 5.04 | 5.04 |