Basic Information
ID: ALA4003511
Type: Binding
Description: Inhibition of JAK1/JAK2 in human whole blood assessed as inhibition of IL-6 induced STAT3 phosphorylation by measuring free compound concentration required for the effect preincubated for 45 mins followed by Il-6 addition and measured after 20 mins by flow cytometric analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4003511
fIC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 566.64 | 5.01 | 5.01 |