Basic Information
ID: ALA4003745
Type: Binding
Description: Inhibition of human HA-tagged SGLT1 expressed in HEK293 cells assessed as decrease in [14C]-AMG uptake measured after 1 to 2 hrs by scintillation counting method
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Sodium/glucose cotransporter 1(ALA4979)
Document: ALA4002600
Inhibition of human HA-tagged SGLT1 expressed in HEK293 cells assessed as decrease in [14C]-AMG uptake measured after 1 to 2 hrs by scintillation counting method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4003745
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 424.95 | 3.17 | 3.17 |
| 530.73 | 2.85 | 2.85 |
| 505.68 | 2.56 | 2.56 |
| 518.63 | 1.19 | 1.19 |
| 627.85 | 2.67 | 2.67 |
| 613.82 | 2.42 | 2.42 |
| 554.11 | 2.82 | 2.82 |
| 611.81 | 2.17 | 2.17 |
| 601.81 | 2.32 | 2.32 |
| 612.83 | 3.90 | 3.90 |
| 629.82 | 2.26 | 2.26 |
| 450.55 | 1.16 | 1.16 |
| 585.77 | 1.64 | 1.64 |
| 546.77 | 3.38 | 3.38 |
| 627.85 | 2.86 | 2.86 |
| 534.68 | 1.88 | 1.88 |
| 599.84 | 2.89 | 2.89 |
| 482.98 | 3.02 | 3.02 |
| 615.84 | 2.67 | 2.67 |