Basic Information
ID: ALA4003765
Type: Binding
Description: Inhibition of CLK mediated SF3B1 activation in human SK-MEL-2 cells assessed as MDM2-pre mRNA exon skipping after 4 hrs by luciferase reporter gene assay relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4003765
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 403.92 | 3.82 | 3.82 |
| 385.90 | 3.93 | 3.93 |
| 385.90 | 3.93 | 3.93 |
| 474.64 | 4.58 | 4.58 |
| 400.92 | 3.55 | 3.55 |
| 399.93 | 4.49 | 4.49 |
| 456.98 | 4.44 | 4.44 |
| 427.94 | 4.10 | 4.10 |
| 399.93 | 4.49 | 4.49 |
| 414.95 | 4.07 | 4.07 |
| 385.90 | 3.93 | 3.93 |
| 414.95 | 4.07 | 4.07 |
| 386.89 | 3.16 | 3.16 |
| 399.93 | 4.49 | 4.49 |
| 360.85 | 3.86 | 3.86 |
| 400.92 | 3.55 | 3.55 |
| 456.98 | 4.44 | 4.44 |
| 414.95 | 4.07 | 4.07 |
| 386.89 | 3.16 | 3.16 |
| 324.17 | 3.09 | 3.09 |
| 399.93 | 4.49 | 4.49 |
| 414.95 | 4.07 | 4.07 |