Basic Information
ID: ALA4003798
Type: Binding
Description: Inhibition of CLK mediated SF3B1 activation in human SK-MEL-2 cells assessed as MDM2-pre mRNA exon skipping at 10 uM after 4 hrs by luciferase reporter gene assay relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4003798
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 331.81 | 5.69 | 5.69 |
| 385.90 | 3.93 | 3.93 |
| 221.04 | 2.46 | 2.46 |
| 230.68 | 1.68 | 1.68 |
| 241.25 | 1.91 | 1.91 |
| 354.36 | 3.63 | 3.63 |
| 311.35 | 2.80 | 2.80 |
| 385.90 | 3.93 | 3.93 |
| 488.67 | 4.92 | 4.92 |
| 399.93 | 4.49 | 4.49 |
| 427.94 | 4.10 | 4.10 |
| 399.93 | 4.49 | 4.49 |
| 414.95 | 4.07 | 4.07 |
| 385.90 | 3.93 | 3.93 |
| 253.75 | 3.70 | 3.70 |
| 399.93 | 4.49 | 4.49 |
| 360.85 | 3.86 | 3.86 |
| 456.98 | 4.44 | 4.44 |
| 310.43 | 3.40 | 3.40 |
| 398.94 | 5.09 | 5.09 |
| 324.17 | 3.09 | 3.09 |
| 399.93 | 4.49 | 4.49 |