Basic Information
ID: ALA4004269
Type: Binding
Description: Inhibition of recombinant perforin (unknown origin) assessed as decrease in lysis of 51Cr-labelled human Jurkat cells by measuring 51Cr release preincubated for 30 mins followed by cell line addition measured after 4 hrs in presence of 0.1% BSA by gamma counting method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4004269
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 483.52 | 4.80 | 4.80 |
| 497.55 | 5.14 | 5.14 |
| 497.55 | 4.84 | 4.84 |
| 523.59 | 6.25 | 6.25 |
| 511.58 | 5.70 | 5.70 |
| 492.51 | 4.48 | 4.48 |
| 497.55 | 4.84 | 4.84 |
| 498.54 | 4.54 | 4.54 |
| 497.55 | 5.08 | 5.08 |
| 483.52 | 4.80 | 4.80 |
| 481.55 | 6.05 | 6.05 |
| 511.58 | 5.18 | 5.18 |
| 497.55 | 5.14 | 5.14 |
| 511.58 | 5.18 | 5.18 |
| 481.48 | 4.67 | 4.67 |
| 483.52 | 5.05 | 5.05 |
| 498.54 | 4.54 | 4.54 |
| 467.52 | 6.04 | 6.04 |