Basic Information
ID: ALA4004557
Type: Binding
Description: Inhibition of PKCtheta in human Jurkat T cells assessed as reduction in anti-CD3/CD28 antibody-induced T-cell activation by measuring decrease in IL-2 secretion after 5 hrs by luciferase reporter gene assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4004557
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 438.49 | 2.43 | 2.43 |
| 443.93 | 4.61 | 4.61 |
| 469.97 | 5.15 | 5.15 |
| 443.93 | 4.61 | 4.61 |
| 429.91 | 4.60 | 4.60 |
| 429.91 | 4.60 | 4.60 |