Basic Information
ID: ALA4004649
Type: Binding
Description: Induction of R-state stabilization of Hb betaGlu6Val mutant in sickle cell disease transfused human whole blood assessed as change from baseline of partial pressure of O2 at which HbS is 50% saturated with O2 at 1 mM preincubated for 45 mins followed by 20 mins oxygenation/deoxygenation cycle by hemoximetry relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4004649
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 352.39 | 3.32 | 3.32 |
| 388.37 | 3.91 | 3.91 |
| 352.39 | 3.32 | 3.32 |
| 321.38 | 3.92 | 3.92 |
| 338.37 | 3.02 | 3.02 |
| 310.31 | 2.06 | 2.06 |
| 324.34 | 2.58 | 2.58 |
| 310.31 | 2.27 | 2.27 |
| 310.31 | 2.27 | 2.27 |
| 396.45 | 3.34 | 3.34 |
| 324.34 | 2.28 | 2.28 |
| 322.37 | 3.31 | 3.31 |
| 338.37 | 2.59 | 2.59 |
| 339.37 | 4.06 | 4.06 |
| 324.38 | 3.51 | 3.51 |
| 338.37 | 3.02 | 3.02 |
| 324.34 | 2.28 | 2.28 |
| 354.37 | 1.73 | 1.73 |
| 337.38 | 3.62 | 3.62 |
| 310.31 | 2.27 | 2.27 |
| 336.40 | 3.62 | 3.62 |
| 312.29 | 1.06 | 1.06 |