Assay Report Card

Basic Information

ID: ALA4004671

Type: Binding

Description: Induction of R-state stabilization of Hb betaGlu6Val mutant in sickle disease patient purified HbS/HbA mixture assessed as change from baseline of partial pressure of O2 at which HbS is 50% saturated with O2 at 500 uM preincubated for 45 mins followed by oxygenation for 10 mins and subsequent deoxygenation by hemoximetry relative to control

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
337.383.623.62