Basic Information
ID: ALA4004674
Type: Binding
Description: Induction of R-state stabilization of Hb betaGlu6Val mutant in sickle disease patient purified HbS/HbA mixture assessed as change from baseline of partial pressure of O2 at which HbS is 50% saturated with O2 at 100 uM preincubated for 45 mins followed by 20 mins oxygenation/deoxygenation cycle by hemoximetry relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4004674
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 243.26 | 2.48 | 2.48 |
| 282.30 | 2.73 | 2.73 |