Basic Information
ID: ALA4005608
Type: Binding
Description: Inhibition of recombinant G9a catalytic SET domain (913 to 1193 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) codon plus RIL assessed as inhibition of methylation activity using biotin-labeled H3 (1 to 25 residues) as substrate and [3H]-SAM after 2 hrs by scintillation proximity assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4005608
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 387.48 | 1.99 | 1.99 |
| 414.55 | 2.30 | 2.30 |
| 385.51 | 3.14 | 3.14 |
| 371.49 | 2.29 | 2.29 |
| 371.49 | 2.75 | 2.75 |
| 401.51 | 2.38 | 2.38 |
| 415.58 | 4.54 | 4.54 |
| 384.52 | 4.20 | 4.20 |
| 401.51 | 2.38 | 2.38 |
| 375.45 | 2.12 | 2.12 |
| 415.54 | 2.77 | 2.77 |
| 373.50 | 3.37 | 3.37 |
| 421.49 | 3.39 | 3.39 |
| 415.58 | 4.17 | 4.17 |
| 401.51 | 2.38 | 2.38 |
| 415.54 | 2.77 | 2.77 |
| 401.56 | 4.15 | 4.15 |
| 415.54 | 2.77 | 2.77 |
| 375.45 | 2.12 | 2.12 |
| 371.49 | 2.29 | 2.29 |
| 413.52 | 2.52 | 2.52 |
| 387.53 | 3.39 | 3.39 |
| 386.50 | 3.05 | 3.05 |
| 399.54 | 3.53 | 3.53 |
| 401.56 | 3.78 | 3.78 |
| 415.54 | 2.77 | 2.77 |
| 387.53 | 3.76 | 3.76 |