Basic Information
ID: ALA4005965
Type: Binding
Description: Inhibition of human topoisomerase-2alpha-mediated relaxation of supercoiled pBR322 DNA after 1 hr by ethidium bromide staining based agarose gel electrophoresis
Format: BAO_0000357
Organism: Homo sapiens
Target: DNA topoisomerase II alpha(ALA1806)
Document: ALA4004831
Inhibition of human topoisomerase-2alpha-mediated relaxation of supercoiled pBR322 DNA after 1 hr by ethidium bromide staining based agarose gel electrophoresis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4005965
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 620.71 | 4.41 | 4.41 |
| 571.68 | 2.94 | 2.94 |
| 614.75 | 2.53 | 2.53 |
| 571.68 | 2.81 | 2.81 |
| 557.65 | 2.55 | 2.55 |
| 630.74 | 3.77 | 3.77 |
| 628.77 | 2.92 | 2.92 |
| 571.68 | 2.94 | 2.94 |
| 642.80 | 3.18 | 3.18 |
| 600.72 | 2.14 | 2.14 |
| 688.83 | 2.94 | 2.94 |
| 500.56 | 2.57 | 2.57 |
| 485.54 | 3.63 | 3.63 |