Basic Information
ID: ALA4005966
Type: Binding
Description: Poison activity at human topoisomerase-2alpha assessed as stabilization of DNA-enzyme cleavage complex at 0.5 to 100 uM using supercoiled pBR322 DNA as substrate after 1 hr by ethidium bromide staining based agarose gel electrophoresis
Format: BAO_0000357
Organism: Homo sapiens
Target: DNA topoisomerase II alpha(ALA1806)
Document: ALA4004831
Poison activity at human topoisomerase-2alpha assessed as stabilization of DNA-enzyme cleavage complex at 0.5 to 100 uM using supercoiled pBR322 DNA as substrate after 1 hr by ethidium bromide staining based agarose gel electrophoresis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4005966
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 571.68 | 2.94 | 2.94 |