Basic Information
ID: ALA4006742
Type: Binding
Description: Inhibition of Brugia malayi T6PP using T6P as substrate assessed as fraction of enzyme unbound with compound by measuring ratio of initial velocities of T6P substrate hydrolysis in presence and absence of compound at 1 mM after 5 mins by BioMol green dye based HTS assay
Organism: Brugia malayi
Activity Charts
Bioactivity
Activity Types for Assay ALA4006742
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 307.31 | -1.08 | -1.08 |
| 342.30 | -5.40 | -5.40 |
| 336.32 | -1.31 | -1.31 |
| 372.30 | -1.03 | -1.03 |
| 364.38 | -2.38 | -2.38 |
| 350.35 | -1.17 | -1.17 |
| 364.33 | -1.50 | -1.50 |
| 364.37 | -0.52 | -0.52 |
| 422.36 | -5.57 | -5.57 |
| 412.42 | 0.36 | 0.36 |
| 351.33 | -1.73 | -1.73 |
| 386.38 | -0.15 | -0.15 |
| 366.34 | -1.82 | -1.82 |
| 366.34 | -1.82 | -1.82 |
| 255.27 | -1.10 | -1.10 |
| 260.22 | -3.39 | -3.39 |
| 336.23 | -1.02 | -1.02 |
| 381.32 | -1.40 | -1.40 |
| 364.37 | -0.52 | -0.52 |
| 366.34 | -1.82 | -1.82 |
| 393.37 | -1.35 | -1.35 |
| 372.44 | -0.01 | -0.01 |
| 364.33 | -1.50 | -1.50 |
| 336.32 | -1.31 | -1.31 |
| 366.34 | -1.82 | -1.82 |
| 424.38 | -1.48 | -1.48 |
| 314.36 | -1.23 | -1.23 |
| 387.37 | -1.26 | -1.26 |
| 364.33 | -1.50 | -1.50 |
| 274.25 | -2.74 | -2.74 |
| 364.37 | -0.52 | -0.52 |
| 448.53 | 1.60 | 1.60 |
| 256.25 | -1.13 | -1.13 |
| 256.25 | -1.13 | -1.13 |