Basic Information
ID: ALA4007219
Type: ADME
Description: Inhibition of human HDAC8 using Boc-Lys(trifluoroacetyl)-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mins by trypsin-based fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4007219
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 508.26 | 4.56 | 4.56 |
| 523.27 | 4.01 | 4.01 |
| 498.20 | 4.08 | 4.08 |
| 494.23 | 4.25 | 4.25 |
| 514.65 | 4.60 | 4.60 |
| 510.23 | 3.95 | 3.95 |
| 494.23 | 4.25 | 4.25 |
| 514.65 | 4.60 | 4.60 |