Basic Information
ID: ALA4007220
Type: ADME
Description: Inhibition of human HDAC4 using Boc-Lys(trifluoroacetyl)-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mins by trypsin-based fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4007220
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 264.32 | 2.47 | 2.47 |
| 480.21 | 3.94 | 3.94 |
| 494.23 | 4.25 | 4.25 |
| 514.65 | 4.60 | 4.60 |
| 537.26 | 3.90 | 3.90 |
| 505.22 | 3.81 | 3.81 |
| 606.10 | 4.55 | 4.55 |
| 508.26 | 4.56 | 4.56 |
| 556.30 | 5.61 | 5.61 |
| 508.26 | 4.50 | 4.50 |
| 604.35 | 6.84 | 6.84 |
| 563.32 | 5.07 | 5.07 |
| 623.35 | 5.19 | 5.19 |
| 530.27 | 5.10 | 5.10 |
| 556.30 | 5.61 | 5.61 |
| 530.27 | 5.10 | 5.10 |
| 556.30 | 5.61 | 5.61 |
| 580.33 | 6.25 | 6.25 |
| 580.33 | 6.25 | 6.25 |
| 580.33 | 6.25 | 6.25 |
| 540.30 | 6.08 | 6.08 |
| 623.35 | 5.19 | 5.19 |
| 523.27 | 4.01 | 4.01 |
| 498.20 | 4.08 | 4.08 |
| 494.23 | 4.25 | 4.25 |
| 514.65 | 4.60 | 4.60 |
| 510.23 | 3.95 | 3.95 |
| 494.23 | 4.25 | 4.25 |
| 514.65 | 4.60 | 4.60 |