Basic Information
ID: ALA4007297
Type: Binding
Description: Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia coli BL21(DE3) using 60 ug/ml single stranded poly(U) RNA as substrate after 30 mins by ADP-Glo luminescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4007297
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 195.60 | 2.52 | 2.52 |
| 175.19 | 2.17 | 2.17 |
| 462.67 | 4.27 | 4.27 |
| 221.23 | 3.13 | 3.13 |
| 217.27 | 3.08 | 3.08 |
| 221.23 | 3.13 | 3.13 |
| 255.68 | 3.78 | 3.78 |
| 203.24 | 2.99 | 2.99 |
| 217.27 | 3.00 | 3.00 |
| 203.24 | 2.99 | 2.99 |
| 203.24 | 2.99 | 2.99 |
| 221.23 | 3.13 | 3.13 |
| 189.21 | 2.43 | 2.43 |
| 202.26 | 2.39 | 2.39 |
| 221.23 | 3.13 | 3.13 |
| 237.69 | 3.64 | 3.64 |
| 237.69 | 3.64 | 3.64 |
| 227.27 | 2.47 | 2.47 |