Basic Information
ID: ALA4007312
Type: Binding
Description: Inhibition of full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 helicase activity expressed in Escherichia coli BL21(DE3) assessed as reduction in RNA unwinding up to 300 uM using (5'-(FITC)-GCUUUACGGUGC-3')/(5'-GGGGAGAAAAACAAAACAAAACUAGCACCGUAAAGCACGC-3') RNA as substrate in presence of ATP/MLN51 after 30 mins by gel electrophoresis method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4007312
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 255.68 | 3.78 | 3.78 |
| 202.26 | 2.39 | 2.39 |