Basic Information
ID: ALA4007648
Type: Binding
Description: Inhibition of Syk in human Ramos B cells assessed as decrease in intracellular calcium flux measured for 3.5 mins by calcium-5 dye based FLIPR assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Tyrosine-protein kinase SYK(ALA2599)
Document: ALA4007384
Inhibition of Syk in human Ramos B cells assessed as decrease in intracellular calcium flux measured for 3.5 mins by calcium-5 dye based FLIPR assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4007648
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 407.35 | 4.05 | 4.05 |
| 320.36 | 3.73 | 3.73 |
| 381.44 | 3.99 | 3.99 |
| 348.29 | 3.82 | 3.82 |
| 421.38 | 4.14 | 4.14 |
| 450.50 | 3.89 | 3.89 |
| 427.81 | 4.43 | 4.43 |
| 474.47 | 3.99 | 3.99 |
| 395.46 | 4.24 | 4.24 |
| 362.32 | 4.13 | 4.13 |
| 377.33 | 3.83 | 3.83 |
| 379.42 | 3.74 | 3.74 |
| 367.41 | 3.60 | 3.60 |
| 419.41 | 4.95 | 4.95 |
| 393.37 | 4.08 | 4.08 |
| 377.45 | 4.55 | 4.55 |
| 381.44 | 3.99 | 3.99 |