Inhibition of CYP3A4 in human liver microsomes assessed as residual activity at 50 uM measured after 30 mins relative to control

Basic Information

ID: ALA4007656

Type: ADME

Description: Inhibition of CYP3A4 in human liver microsomes assessed as residual activity at 50 uM measured after 30 mins relative to control

Format: BAO_0000019

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: Microsomes

Target:  Cytochrome P450 3A4(ALA340)

Document:  ALA4007384

Inhibition of CYP3A4 in human liver microsomes assessed as residual activity at 50 uM measured after 30 mins relative to control: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
320.363.733.73
421.384.144.14
379.423.743.74