Basic Information
ID: ALA4008166
Type: Binding
Description: Inhibition of recombinant N-terminal GST-tagged EED (76 to 441 residues) (unknown origin) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIL assessed as reduction in SAH production using H3[21-44,K27Me0) peptide as substrate measured after 20 mins by LC/MS/MS method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4008166
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 264.30 | 3.40 | 3.40 |
| 572.75 | 4.73 | 4.73 |
| 382.47 | 3.94 | 3.94 |
| 290.33 | 3.60 | 3.60 |
| 239.24 | 1.81 | 1.81 |
| 422.95 | 4.66 | 4.66 |
| 406.49 | 4.14 | 4.14 |
| 369.41 | 2.40 | 2.40 |
| 378.51 | 3.83 | 3.83 |
| 315.34 | 3.47 | 3.47 |
| 349.40 | 2.45 | 2.45 |
| 290.33 | 3.60 | 3.60 |
| 358.45 | 3.47 | 3.47 |
| 349.40 | 2.45 | 2.45 |
| 402.53 | 4.31 | 4.31 |
| 372.43 | 3.53 | 3.53 |
| 290.33 | 3.60 | 3.60 |
| 398.92 | 4.18 | 4.18 |
| 348.41 | 3.06 | 3.06 |
| 323.79 | 2.81 | 2.81 |
| 388.48 | 3.47 | 3.47 |
| 349.40 | 2.45 | 2.45 |
| 402.53 | 4.31 | 4.31 |
| 373.42 | 2.93 | 2.93 |
| 372.43 | 3.53 | 3.53 |
| 291.31 | 3.00 | 3.00 |
| 333.33 | 3.61 | 3.61 |
| 373.42 | 2.93 | 2.93 |
| 384.44 | 3.36 | 3.36 |
| 378.51 | 3.83 | 3.83 |
| 289.34 | 4.21 | 4.21 |
| 364.48 | 3.53 | 3.53 |
| 388.50 | 4.00 | 4.00 |
| 412.50 | 3.95 | 3.95 |
| 373.42 | 2.93 | 2.93 |
| 374.45 | 3.59 | 3.59 |
| 382.47 | 3.67 | 3.67 |
| 291.31 | 3.00 | 3.00 |
| 348.41 | 3.06 | 3.06 |