Basic Information
ID: ALA4008434
Type: Binding
Description: Inhibition of recombinant human TACE extracellular domain (215 to 671 residues) assessed as inhibition of proteolytic activity preincubated for 30 mins prior to addition of Mca-Pro-Leu-Ala-Gln-Ala-Val-Dpa-Arg-Ser-Ser-Ser-Arg-NH2 as substrate measured every 2 mins for 3 hrs in presence of 0.1% BSA by fluorescence analysis
Format: BAO_0000357
Organism: Homo sapiens
Target: ADAM17(ALA3706)
Document: ALA4007405
Inhibition of recombinant human TACE extracellular domain (215 to 671 residues) assessed as inhibition of proteolytic activity preincubated for 30 mins prior to addition of Mca-Pro-Leu-Ala-Gln-Ala-Val-Dpa-Arg-Ser-Ser-Ser-Arg-NH2 as substrate measured every 2 mins for 3 hrs in presence of 0.1% BSA by fluorescence analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4008434
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 2168.69 | ||
| 2180.75 | ||
| 2081.61 | ||
| 2095.64 | ||
| 2340.88 | ||
| 2413.94 | ||
| 2083.54 | ||
| 2267.83 | ||
| 2139.65 | ||
| 2154.67 |