Basic Information
ID: ALA4008437
Type: Binding
Description: Inhibition of recombinant human complement factor D catalytic domain (G24 to A253 residues) expressed in Escherichia coli Rosetta using Z-Lys-thiobenzyl as substrate pretreated for 1 hr followed by substrate addition by 2,4-dinitrobenzenesulfonyl-2,7-desmethyl-fluorescein probe based spectrofluorimetric thioesterolysis assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Complement factor D(ALA2176771)
Document: ALA4007406
Inhibition of recombinant human complement factor D catalytic domain (G24 to A253 residues) expressed in Escherichia coli Rosetta using Z-Lys-thiobenzyl as substrate pretreated for 1 hr followed by substrate addition by 2,4-dinitrobenzenesulfonyl-2,7-desmethyl-fluorescein probe based spectrofluorimetric thioesterolysis assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4008437
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 451.40 | 4.01 | 4.01 |
| 465.43 | 3.68 | 3.68 |
| 465.43 | 4.32 | 4.32 |