Assay Report Card

Basic Information

ID: ALA4008508

Type: Functional

Description: In vivo inhibition of NAMPT in DNBS-induced BALB/c mouse colitis model assessed as reduction in neutrophil infiltration by measuring myeloperoxidase levels at 20 mg/kg, ip bid administered for 3 days post DNBS challenge by ELISA

Organism: Mus musculus

Strain: BALB/c

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
392.471.901.90
391.523.933.93
398.515.655.65