Basic Information
ID: ALA4008514
Type: Binding
Description: Inhibition of human full length GST-tagged PDE2a using FAM-labeled cAMP as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by IMAP assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4008514
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 376.46 | 2.78 | 2.78 |
| 501.25 | 3.44 | 3.44 |
| 407.37 | 3.28 | 3.28 |
| 362.44 | 2.47 | 2.47 |
| 454.25 | 3.60 | 3.60 |
| 371.44 | 3.61 | 3.61 |
| 353.40 | 2.90 | 2.90 |
| 365.44 | 2.77 | 2.77 |
| 386.46 | 3.44 | 3.44 |
| 454.25 | 3.60 | 3.60 |
| 371.44 | 3.61 | 3.61 |
| 415.42 | 3.71 | 3.71 |
| 454.25 | 3.60 | 3.60 |
| 409.80 | 3.49 | 3.49 |
| 430.43 | 3.49 | 3.49 |
| 363.42 | 2.39 | 2.39 |
| 372.43 | 3.00 | 3.00 |
| 375.35 | 2.84 | 2.84 |
| 401.42 | 3.01 | 3.01 |
| 361.45 | 2.94 | 2.94 |
| 371.44 | 3.61 | 3.61 |
| 393.34 | 2.98 | 2.98 |
| 400.87 | 2.95 | 2.95 |
| 407.42 | 3.85 | 3.85 |